Clinical Analysis of Intravenous Gammaglobulin in Combination with Methylprednisolone on 16 Cases of Sever Bullous Drug Eruption 丙种球蛋白联合甲泼尼龙治疗重症大疱型药疹16例临床分析
Methods 23 patients with the lesions were collected and analyzed by means of their clinical feature, laboratory and histopathology, and differentiated to anaphylactoid purpura, allergic cutaneous vasculitis, bullous erythema multiforme and fixed drug eruption. 方法对23例紫癜型药疹从临床、实验室及组织病理三方面进行分析,并与过敏性紫癜、变应性血管炎、大疱性多形红斑和固定性药疹相鉴别。
Results The primary diseases were connective tissue diseases, bullous dermatoses, and severe drug eruption, and the predominant causes of death were severe infection and multiple organ failure. 结果原发疾病主要为结缔组织病、大疱性皮肤病、重症药疹;死亡原因主要为严重感染和多器官功能衰竭。
Objective: To analyze the clinical features and therapeutic effects on bullous epidermal necrolysis type drug eruption in order to improve clinical management of the disease. 目的:探讨大疱性表皮坏死松解型药疹的临床特征及治疗效果以指导今后临床。